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Osteosarcoma pipeline insights

Osteosarcoma Pipeline constitutes 25+ key companies continuously working towards developing 30+ Osteosarcoma treatment therapies, analyzes DelveInsight.

Osteosarcoma Overview:

Osteosarcoma, or osteogenic sarcoma, is a rare form of bone cancer that originates in the bones, particularly the long bones near the knee and shoulder. It mainly affects children and teenagers during their growth periods. While the exact cause is not fully known, there is sometimes a genetic predisposition that increases the risk. The primary symptom of osteosarcoma is pain, which may start intermittently but typically becomes persistent. Swelling, the appearance of a lump near the tumor, or limping (if the leg bones are affected) may also occur. Some cases of osteosarcoma may not show symptoms, complicating early detection.

Diagnosis involves a detailed review of medical history, physical examination, and various imaging tests, such as X-rays, CT scans, MRIs, bone scans, and PET scans. A biopsy of the suspected tumor is necessary to confirm the diagnosis. Treatment generally consists of a combination of chemotherapy, surgery, and, in some cases, radiation therapy. Chemotherapy is often given before surgery to shrink the tumor for easier removal, and it may be used afterward to eliminate any remaining cancer cells. Radiation therapy, while not commonly used, may serve as an alternative to surgery in specific cases.

The prognosis for osteosarcoma depends on factors such as cancer stage, tumor location, and the patient’s overall health. Early detection and a multidisciplinary treatment team, including oncologists, surgeons, and other specialists, are essential for better outcomes. Patients may require limb-sparing surgery, amputation for more severe cases, or rotationplasty for tumors near the knee. These surgical procedures aim to remove the cancer while preserving limb function and quality of life. Ongoing research is focused on creating more effective chemotherapy treatments and targeted therapies to improve the results for osteosarcoma patients.

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“Osteosarcoma Pipeline Insight 2025” report by DelveInsight provides a comprehensive analysis of the ongoing clinical development activities and growth prospects across the Osteosarcoma Therapeutics Market.

Key Takeaways from the Osteosarcoma Pipeline Report

• DelveInsight’s Osteosarcoma pipeline report depicts a robust space with 25+ active players working to develop 30+ pipeline therapies for Osteosarcoma treatment.

• In January 2025, The FDA awarded breakthrough therapy designation (BTD) to GSK5764227 (GSK’227) for treating adult patients with relapsed or refractory osteosarcoma who have experienced disease progression after receiving at least two previous treatment regimens.

• Key Osteosarcoma companies such as AlaMab Therapeutics, Zentalis Pharmaceuticals, Isofol Medical, Merck, Eisai Co Ltd, Jiangsu Hengrui Medicine, AstraZeneca, Y-mAbs Therapeutics, Innovent Biologics, PersonGen BioTherapeutics (Suzhou), Cellectar Biosciences, Inc., MacroGenics, Shanghai Pharmaceuticals Holding, Celgene, Hutchmed, MedImmune LLC, Lee’s Pharmaceutical Limited, EMD Serono, Iovance Biotherapeutics, Inc., BioEclipse Therapeutics, BioAtla, Inc., Celgene, Actuate Therapeutics Inc., and others are evaluating new drugs for Osteosarcoma to improve the treatment landscape.

• Promising Osteosarcoma pipeline therapies in various stages of development include ALMB 0168, ZN c3, Arfolitixorin, Lenvatinib, Camrelizumab, Ceralasertib, Humanized anti-GD2 antibody, Targeting CD276 CAR T cells, CLR- 131, Pembrolizumab, Surufatinib, Enoblituzumab, Durvalumab, ZKAB001, M6620, Aldesleukin, CRX100, CAB-AXL-ADC, CC-486, CC-115, 9-ING-41, Palbociclib, and others.

Osteosarcoma Pipeline Analysis

The report provides insights into:

• The report provides detailed insights into the key companies that are developing therapies in the Osteosarcoma Market.

• The report also evaluates different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Osteosarcoma treatment.

• It analyzes the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

• It navigates the emerging drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement, and financing details for future advancement of the Osteosarcoma market.

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Osteosarcoma Emerging Drugs

• HS-20093: Hansoh BioMedical R&D Company

• ZN c3: Zentalis Pharmaceuticals

• NPX267: Nextpoint Therapeutics

Osteosarcoma Companies

There are over 25 major companies focused on developing therapies for Osteosarcoma. Among them, Hansoh BioMedical R&D Company is one of the organizations with drug candidates for Osteosarcoma in the most advanced stage, specifically Phase III.

DelveInsight’s report covers around 22+ products under different phases of clinical development like

• Late stage products (Phase III)

• Mid-stage products (Phase II)

• Early-stage product (Phase I) along with the details of

• Pre-clinical and Discovery stage candidates

• Discontinued & Inactive candidates

Osteosarcoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

• Intravenous

• Subcutaneous

• Oral

• Intramuscular

Osteosarcoma Products have been categorized under various Molecule types such as

• Monoclonal antibody

• Small molecule

• Peptide

Download Sample Pages to Get an in-depth Assessment of the Emerging Osteosarcoma Therapies and Key Companies: Osteosarcoma Clinical Trials and advancements

Osteosarcoma Pipeline Therapeutic Assessment

• Osteosarcoma Assessment by Product Type

• Osteosarcoma By Stage

• Osteosarcoma Assessment by Route of Administration

• Osteosarcoma Assessment by Molecule Type

Download Osteosarcoma Sample report to know in detail about the Osteosarcoma treatment market @ Osteosarcoma Therapeutic Assessment

Table of Content

1. Report Introduction

2. Executive Summary

3. Osteosarcoma Current Treatment Patterns

4. Osteosarcoma – DelveInsight’s Analytical Perspective

5. Therapeutic Assessment

6. Osteosarcoma Late-Stage Products (Phase-III)

7. Osteosarcoma Mid-Stage Products (Phase-II)

8. Early Stage Products (Phase-I)

9. Pre-clinical Products and Discovery Stage Products

10. Inactive Products

11. Dormant Products

12. Osteosarcoma Discontinued Products

13. Osteosarcoma Product Profiles

14. Osteosarcoma Key Companies

15. Osteosarcoma Key Products

16. Dormant and Discontinued Products

17. Osteosarcoma Unmet Needs

18. Osteosarcoma Future Perspectives

19. Osteosarcoma Analyst Review

20. Appendix

21. Report Methodology

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